产品编号 | 产品名称 | CAS No. |
DC9993 |
MK-8998
MK-8998 (compound 33) 是有效的,选择性的T型钙通道抑制剂。 |
953778-58-0 |
DCAPI1140 |
Bumetanide
Bumetanide (Ro 10-6338;PF 1593) 是一种 Na+-K+-Cl- 协同转运蛋白 1 (NKCC1) 抑制剂,对 NKCC2 的抑制作用较弱,对 hNKCC1A 和 hNKCC2A 的 IC50 值分别为 0.68 和 4.0 μM。 |
28395-03-1 |
DC9378 |
Efonidipine (hydrochloride monoethanolate)
Efonidipine hydrochloride monoethanolate (NZ-105 hydrochloride monoethanolate) 是T型和L型钙离子通道双重阻断剂。 |
111011-76-8 |
DC11144 |
NBI-59159
NBI-59159 (NBI59159) is a potent EAAT3-preferring inhibitor.. |
1026096-83-2 |
DC8902 |
PNU282987
PNU282987 in stock,price: 350 USD/100mg. PNU-282987 is a selective α7 nicotinic acetylcholine receptor(α7 nAChR) agonist with Ki of 26 nM; no affinity for α1β1γδ and α3β4 nAChRs (IC50 ≥ 60? |
123464-89-1 |
DC11247 |
Nelonicline
Nelonicline (ABT-126) is a potent, selective α7 nicotinic receptor (nAChR) partial agonist for the treatment of cognitive impairment with schizophrenia.. |
1026134-63-3 |
DC28701 |
nAChR agonist 1
nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). |
1394371-75-5 |
DC4171 |
Escitalopram oxalate
Escitalopram Oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM. |
219861-08-2 |
DC9098 |
Paroxetine HCl
Paroxetine hydrochloride hemihydrate is a antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). |
110429-35-1 |
DC10382 |
Farampator
Farampator (CX-691;Org24448) is an AMPA receptor positive modulator. |
211735-76-1 |
DC3111 |
Canagliflozin
Canagliflozin is a highly potent and selective SGLT2 inhibitor for CHO-hSGLT2, CHO-rSGLT2 and CHO-mSGLT2 with IC50 of 4.4 nM, 3.7 nM and 2 nM, respectively. |
842133-18-0 |
DC6904 |
DAPAGLIFLOZIN
DAPAGLIFLOZIN is a SGLT-2 inhibitor. |
461432-26-8 |
DC7463 |
Mibefradil-dihydrochloride
Mibefradil 2Hcl(Ro 40-5967) is calcium channel blocker with moderate selectivity for T-type Ca2+ channels displaying IC50 values of 2.7 μM and 18.6 μM for T-type and L-type channels respectively. |
116666-63-8 |
DC7588 |
PNU120596
PNU-120596 is a positive allosteric modulator of α7 nAChR with EC50 of 216 nM. |
501925-31-1 |
DC7755 |
TRCP6 inhibitor(SAR7334)
TRPC6 inhibitor is a potent TRPC6(Transient receptor potential cation channel, subfamily C, member 6) inhibitor. |
1333207-63-8 |
DC7833 |
NS309
NS309 is a positive modulator of small- and intermediate- conductance Ca2+-activated K+ channels (KCa2 and KCa3.1 channels); increases Ca2+ sensitivity. Displays no activity at BK channels. |
18711-16-5 |
DC7989 |
PEPA
PEPA is an allosteric modulator of AMPA receptors; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity. |
141286-78-4 |
DC8429 |
Verdinexor (KPT-335)
Verdinexor (KPT-335) is an orally bioavailable, selective XPO1/CRM1 inhibitor. |
1392136-43-4 |
DC8457 |
BMS-309403
BMS309403 is orally active, reducing atherosclerosis in mice lacking apoplipoprotein E. |
300657-03-8 |
DC8954 |
Gabapentin
Gabapentin (Neurontin) is a pharmaceutical drug, specifically a GABA analog. It was originally developed to treat epilepsy, and currently is also used to relieve neuropathic pain. |
60142-96-3 |
DC9082 |
Chlorpromazine HCl
Chlorpromazine Hydrochloride is a dopamine and potassium channel inhibitor used as the prototypical phenothiazine antipsychotic drug. |
69-09-0 |
DC9600 |
Senicapoc
Senicapoc(ICA17043) is a potent and selective Gardos channel blocker; blocked Ca(2+)-induced rubidium flux from human RBCs/ inhibited RBC dehydration with IC50s of 11 nM/30 nM, respectively. IC50 value: 11/30 nM [1] Target: Gardos channel in vitro: I |
289656-45-7 |