Animal Experiment Dose Converter
Equivalent dose conversion in different experimental animals(Data from FDA guidelines)
| Weight (kg) |
0.02 |
0.15 |
1.8 |
0.4 |
0.08 |
10 |
| Body surface area (m2) |
0.007 |
0.025 |
0.15 |
0.05 |
0.02 |
0.5 |
| KmCoefficient |
3 |
6 |
12 |
8 |
5 |
20 |
Conversion method based on body surface area, for example, to use adriamycin rat dose of 10 mg/kg dose conversion into mice, need to be 10 mg/kg Km multiplied by the coefficient of rats (6), divided by coefficient of Km mice (3), get the equivalent dose of adriamycin for mice to 20 mg/kg.
