TH-263 is an inactive analog control for the type III allosteric LIM-kinase (LIMK) inhibitors TH-257, TH-255 and TH-251.

Vanin-1-IN-1 是一种 vanin-1 酶抑制剂。vanin-1 是一种细胞表面相关的肌醇 (GPi) 锚定蛋白，在代谢和炎症中发挥重要作用。

VBIT-12 is a potent inhibitor of VDAC1, directly interacting with purified VDAC1 and reducing its channel conductance.

VU6015929 是一种有效的，选择性的，口服活性的 DDR1/2 抑制剂，IC50 分别为 4.67 nM 和 7.39 nM。VU6015929 有效地阻止胶原蛋白诱导的 DDR1 激活和 IV 型胶原蛋白的产生。

The compound (Akt-I-1,2) inhibited both Akt1 and Akt2 with IC50 values of 2.7 and 21 μM respectively.

Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM.

Nelfinavir(AG-1341) is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor (Ki=2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection.

Sitravatinib (MGCD516) is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl.

ATH686 (ATH-686) is a potent and selective, second-generation inhibitor of mutant FLT3 protein kinase.

Danicopan (ACH-4471,) is a highly potent, orally active Factor D inhibitor with Kd of 0.54 nM.

Tavapadon is a potent, orally-bioavailable, selective partial agonist of the dopamine D1 and D5 receptors.

Hoechst染料是DNA蓝色荧光染料，Hoechst 33342是其中一种。

Nelonicline (ABT-126) is a potent, selective α7 nicotinic receptor (nAChR) partial agonist for the treatment of cognitive impairment with schizophrenia..

A novel anti-TB agent that has an MIC range of 0.06-0.5 ug/mL..

A potent, selective, orally availale C5aR (CD88) inhibitor with IC50 of 0.1 nM.

A potent, selective, reversible Cdc25 dual specificity phosphatase inhibitor with Ki of 32/96/40 nM for Cdc25A/B/C, respectively.

UE2343 (UE-2343, Xanamem) is a potent, orally bioavailable, brain penetrant 11β-HSD1 inhibitor with IC50 of 24 nM in cell-free assays, with no activity for isozyme 11β-HSD2.

HM30181 mesylate is a competitive and potent P-glycoprotein inhibitor.

Pyronaridine tetraphosphate is a Mannich base anti-malarial with demonstrated efficacy against drug resistant Plasmodium falciparum, P. vivax, P. ovale and P. malariae.

BI-409306 is a potent and selective PDE9A inhibitor, with an IC50 of 52 nM, and shows weak activity against other PDEs.

SB297006 is a CCR3 antagonist, which significantly inhibits proliferation and neurosphere formation in CCL11-treated neural progenitor cells.

BF 227 is a candidate for an amyloid imaging probe for PET, with a Ki of 4.3 nM for Aβ1-42 fibrils.