T863

产品编号: DC8058 Featured
T863
结构式
701232-20-4
此产品仅供科研所需,我们不出售给病人
​我们将匹配市场上最好的价格给您
Email:order@dcbio.cn
免费咨询电话:4008862077
我们的合作伙伴:
  • 20
  • 19
  • 18
  • 17
  • 16
  • 15
  • 14
  • 12
  • 11
  • 10
  • 9
  • 8
  • 13
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
中国地区超过5000个高品质化合物库存
应用领域
T863 是选择性,有口服活性的二酰基甘油酰基转移酶1 (DGAT1) 抑制剂,能结合DGAT1的酰基辅酶A结合位点,抑制三酰甘油在细胞内的合成。
Cas No.: 701232-20-4
名称: trans-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]-cyclohexaneacetic acid
别名: T-863,T 863
SMILES: [C@@H](CC(O)=O)1CC[C@H](C2=CC=C(C3C(C)(C)OC4=NC=NC(N)=C4N=3)C=C2)CC1
分子式: C22H26N4O3
分子量: 394.47
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. T863 causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice. For the detailed information of T863, the solubility of T863 in water, the solubility of T863 in DMSO, the solubility of T863 in PBS buffer, the animal experiment (test) of T863, the cell expriment (test) of T863, the in vivo, in vitro and clinical trial test of T863, the EC50, IC50,and affinity,of T863, For the detailed information of T863, the solubility of T863 in water, the solubility of T863 in DMSO, the solubility of T863 in PBS buffer, the animal experiment (test) of T863, the cell expriment (test) of T863, the in vivo, in vitro and clinical trial test of T863, the EC50, IC50,and affinity,of T863, Please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
产品编号 产品名称 应用领域
DC8058 T863 T863 是选择性,有口服活性的二酰基甘油酰基转移酶1 (DGAT1) 抑制剂,能结合DGAT1的酰基辅酶A结合位点,抑制三酰甘油在细胞内的合成。