2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
T863 is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. T863 causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice. For the detailed information of T863, the solubility of T863 in water, the solubility of T863 in DMSO, the solubility of T863 in PBS buffer, the animal experiment (test) of T863, the cell expriment (test) of T863, the in vivo, in vitro and clinical trial test of T863, the EC50, IC50,and affinity,of T863, For the detailed information of T863, the solubility of T863 in water, the solubility of T863 in DMSO, the solubility of T863 in PBS buffer, the animal experiment (test) of T863, the cell expriment (test) of T863, the in vivo, in vitro and clinical trial test of T863, the EC50, IC50,and affinity,of T863, Please contact DC Chemicals.