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Potent, ATP-competitive Raf kinase inhibitor (IC50 = 10 nM) that displays > 7, > 30 and > 70-fold selectivity over p38α, GSK3β and Lck respectively. Suppresses DNA synthesis and induces apoptosis in cells that proliferate in response to Raf-1 and A-Raf but not B-Raf. For the detailed information of L-779,450, the solubility of L-779,450 in water, the solubility of L-779,450 in DMSO, the solubility of L-779,450 in PBS buffer, the animal experiment (test) of L-779,450, the cell expriment (test) of L-779,450, the in vivo, in vitro and clinical trial test of L-779,450, the EC50, IC50,and affinity,of L-779,450, For the detailed information of L-779,450, the solubility of L-779,450 in water, the solubility of L-779,450 in DMSO, the solubility of L-779,450 in PBS buffer, the animal experiment (test) of L-779,450, the cell expriment (test) of L-779,450, the in vivo, in vitro and clinical trial test of L-779,450, the EC50, IC50,and affinity,of L-779,450, Please contact DC Chemicals. |