L-779,450 产品说明书 Chemicals
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产品编号 DC8362
名称 L-779,450

化学性质

CAS 303727-31-3
分子式 C20H14CLN3O
分子量 347.8
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Potent, ATP-competitive Raf kinase inhibitor (IC50 = 10 nM) that displays > 7, > 30 and > 70-fold selectivity over p38α, GSK3β and Lck respectively. Suppresses DNA synthesis and induces apoptosis in cells that proliferate in response to Raf-1 and A-Raf but not B-Raf. For the detailed information of L-779,450, the solubility of L-779,450 in water, the solubility of L-779,450 in DMSO, the solubility of L-779,450 in PBS buffer, the animal experiment (test) of L-779,450, the cell expriment (test) of L-779,450, the in vivo, in vitro and clinical trial test of L-779,450, the EC50, IC50,and affinity,of L-779,450, For the detailed information of L-779,450, the solubility of L-779,450 in water, the solubility of L-779,450 in DMSO, the solubility of L-779,450 in PBS buffer, the animal experiment (test) of L-779,450, the cell expriment (test) of L-779,450, the in vivo, in vitro and clinical trial test of L-779,450, the EC50, IC50,and affinity,of L-779,450, Please contact DC Chemicals.
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