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NU 6027 inhibits both CDK1 and CDK2 with IC50 values of 2.9 and 2.2 µM, respectively. It has been shown to inhibit cellular ataxia telangiectasia mutated and Rad3-realted kinase activity (IC50 = 6.7 µM) and impair G2/M arrest in various human cancer cells, potentiating the cytotoxic effects of DNA-damaging, anticancer agents such as cisplatin. For the detailed information of NU6027, the solubility of NU6027 in water, the solubility of NU6027 in DMSO, the solubility of NU6027 in PBS buffer, the animal experiment (test) of NU6027, the cell expriment (test) of NU6027, the in vivo, in vitro and clinical trial test of NU6027, the EC50, IC50,and affinity,of NU6027, For the detailed information of NU6027, the solubility of NU6027 in water, the solubility of NU6027 in DMSO, the solubility of NU6027 in PBS buffer, the animal experiment (test) of NU6027, the cell expriment (test) of NU6027, the in vivo, in vitro and clinical trial test of NU6027, the EC50, IC50,and affinity,of NU6027, Please contact DC Chemicals. |