NU6027 产品说明书 Chemicals
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产品编号 DC8214
名称 NU6027

化学性质

CAS 220036-08-8
分子式 C11H17N5O2
分子量 251.29
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


NU 6027 inhibits both CDK1 and CDK2 with IC50 values of 2.9 and 2.2 µM, respectively. It has been shown to inhibit cellular ataxia telangiectasia mutated and Rad3-realted kinase activity (IC50 = 6.7 µM) and impair G2/M arrest in various human cancer cells, potentiating the cytotoxic effects of DNA-damaging, anticancer agents such as cisplatin. For the detailed information of NU6027, the solubility of NU6027 in water, the solubility of NU6027 in DMSO, the solubility of NU6027 in PBS buffer, the animal experiment (test) of NU6027, the cell expriment (test) of NU6027, the in vivo, in vitro and clinical trial test of NU6027, the EC50, IC50,and affinity,of NU6027, For the detailed information of NU6027, the solubility of NU6027 in water, the solubility of NU6027 in DMSO, the solubility of NU6027 in PBS buffer, the animal experiment (test) of NU6027, the cell expriment (test) of NU6027, the in vivo, in vitro and clinical trial test of NU6027, the EC50, IC50,and affinity,of NU6027, Please contact DC Chemicals.
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