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An ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFRK), with an IC50 of 25 pM. Inhibits other tyrosine kinases at micromolar or higher concentrations. It selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression and oncogenic transformation. Inhibits the growth of a number of cancer cell lines. An extremely useful tool for exploring EGF-mediated cellular signaling. For the detailed information of PD 153035(AG-1517), the solubility of PD 153035(AG-1517) in water, the solubility of PD 153035(AG-1517) in DMSO, the solubility of PD 153035(AG-1517) in PBS buffer, the animal experiment (test) of PD 153035(AG-1517), the cell expriment (test) of PD 153035(AG-1517), the in vivo, in vitro and clinical trial test of PD 153035(AG-1517), the EC50, IC50,and affinity,of PD 153035(AG-1517), For the detailed information of PD 153035(AG-1517), the solubility of PD 153035(AG-1517) in water, the solubility of PD 153035(AG-1517) in DMSO, the solubility of PD 153035(AG-1517) in PBS buffer, the animal experiment (test) of PD 153035(AG-1517), the cell expriment (test) of PD 153035(AG-1517), the in vivo, in vitro and clinical trial test of PD 153035(AG-1517), the EC50, IC50,and affinity,of PD 153035(AG-1517), Please contact DC Chemicals. |
