2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
An ultra-potent inhibitor of epidermal growth factor receptor tyrosine kinase (EGFRK), with an IC50 of 25 pM. Inhibits other tyrosine kinases at micromolar or higher concentrations. It selectively blocks EGF-mediated cellular processes including mitogenesis, early gene expression and oncogenic transformation. Inhibits the growth of a number of cancer cell lines. An extremely useful tool for exploring EGF-mediated cellular signaling. For the detailed information of PD 153035(AG-1517), the solubility of PD 153035(AG-1517) in water, the solubility of PD 153035(AG-1517) in DMSO, the solubility of PD 153035(AG-1517) in PBS buffer, the animal experiment (test) of PD 153035(AG-1517), the cell expriment (test) of PD 153035(AG-1517), the in vivo, in vitro and clinical trial test of PD 153035(AG-1517), the EC50, IC50,and affinity,of PD 153035(AG-1517), For the detailed information of PD 153035(AG-1517), the solubility of PD 153035(AG-1517) in water, the solubility of PD 153035(AG-1517) in DMSO, the solubility of PD 153035(AG-1517) in PBS buffer, the animal experiment (test) of PD 153035(AG-1517), the cell expriment (test) of PD 153035(AG-1517), the in vivo, in vitro and clinical trial test of PD 153035(AG-1517), the EC50, IC50,and affinity,of PD 153035(AG-1517), Please contact DC Chemicals.
