Cas No.: | 1234563-16-6 |
名称: | |
别名: | AN 3365,AN-3365 |
SMILES: | OCCCOC1=C(B(O)O[C@@H]2CN)C2=CC=C1.[H]Cl |
分子式: | C11H16BNO4.HCl |
分子量: | 273.52 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
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In Vitro: | |
References: | AN3365 is a novel boron-based, small-molecule product candidate that targets the bacterial enzyme leucyl tRNA synthetase. Preclinical studies suggest that AN3365 is a promising compound for the treatment of infections caused by a broad range of Gramnegative bacteria, including E. coli, K. pneumoniae, Citrobacter spp, S.marcescens, P.vulgaris, Providentia spp and Enterobacter spp. AN3365 has demonstrated a potent effect on strains harboring known resistance to widely-used antibiotics. |
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Animal Administration: | |
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