2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
AN3365 is a novel boron-based, small-molecule product candidate that targets the bacterial enzyme leucyl tRNA synthetase. Preclinical studies suggest that AN3365 is a promising compound for the treatment of infections caused by a broad range of Gramnegative bacteria, including E. coli, K. pneumoniae, Citrobacter spp, S.marcescens, P.vulgaris, Providentia spp and Enterobacter spp. AN3365 has demonstrated a potent effect on strains harboring known resistance to widely-used antibiotics.
