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Potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2). Inhibits both G2019S mutant and wild-type LRRK2 kinase activity (IC50 values are 6 and 13 nM respectively). Causes dephosphorylation, ubiquitination and degradation of LRRK2. For the detailed information of LRRK2-IN-1, the solubility of LRRK2-IN-1 in water, the solubility of LRRK2-IN-1 in DMSO, the solubility of LRRK2-IN-1 in PBS buffer, the animal experiment (test) of LRRK2-IN-1, the cell expriment (test) of LRRK2-IN-1, the in vivo, in vitro and clinical trial test of LRRK2-IN-1, the EC50, IC50,and affinity,of LRRK2-IN-1, For the detailed information of LRRK2-IN-1, the solubility of LRRK2-IN-1 in water, the solubility of LRRK2-IN-1 in DMSO, the solubility of LRRK2-IN-1 in PBS buffer, the animal experiment (test) of LRRK2-IN-1, the cell expriment (test) of LRRK2-IN-1, the in vivo, in vitro and clinical trial test of LRRK2-IN-1, the EC50, IC50,and affinity,of LRRK2-IN-1, Please contact DC Chemicals. |