2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
Potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2). Inhibits both G2019S mutant and wild-type LRRK2 kinase activity (IC50 values are 6 and 13 nM respectively). Causes dephosphorylation, ubiquitination and degradation of LRRK2. For the detailed information of LRRK2-IN-1, the solubility of LRRK2-IN-1 in water, the solubility of LRRK2-IN-1 in DMSO, the solubility of LRRK2-IN-1 in PBS buffer, the animal experiment (test) of LRRK2-IN-1, the cell expriment (test) of LRRK2-IN-1, the in vivo, in vitro and clinical trial test of LRRK2-IN-1, the EC50, IC50,and affinity,of LRRK2-IN-1, For the detailed information of LRRK2-IN-1, the solubility of LRRK2-IN-1 in water, the solubility of LRRK2-IN-1 in DMSO, the solubility of LRRK2-IN-1 in PBS buffer, the animal experiment (test) of LRRK2-IN-1, the cell expriment (test) of LRRK2-IN-1, the in vivo, in vitro and clinical trial test of LRRK2-IN-1, the EC50, IC50,and affinity,of LRRK2-IN-1, Please contact DC Chemicals.
