| References: |
In normal rats and dogs a saturable urinary glucose excretion was produced with an ED50 of 0.38 and 0.09 mg/kg, respectively.
EGT1442 significantly prolonged the median survival of SHRSP rats.
EGT1442 dose-dependently reduced HbA1c and blood glucose concentration without affecting body mass or insulin level. For the detailed information of Bexagliflozin(THR1442), the solubility of Bexagliflozin(THR1442) in water, the solubility of Bexagliflozin(THR1442) in DMSO, the solubility of Bexagliflozin(THR1442) in PBS buffer, the animal experiment (test) of Bexagliflozin(THR1442), the cell expriment (test) of Bexagliflozin(THR1442), the in vivo, in vitro and clinical trial test of Bexagliflozin(THR1442), the EC50, IC50,and affinity,of Bexagliflozin(THR1442), For the detailed information of Bexagliflozin(THR1442), the solubility of Bexagliflozin(THR1442) in water, the solubility of Bexagliflozin(THR1442) in DMSO, the solubility of Bexagliflozin(THR1442) in PBS buffer, the animal experiment (test) of Bexagliflozin(THR1442), the cell expriment (test) of Bexagliflozin(THR1442), the in vivo, in vitro and clinical trial test of Bexagliflozin(THR1442), the EC50, IC50,and affinity,of Bexagliflozin(THR1442), Please contact DC Chemicals. |
