Bexagliflozin(THR1442,EGT1442)| 产品说明书 Chemicals
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产品编号 DC8186
名称 Bexagliflozin(THR1442,EGT1442)|

化学性质

CAS 1118567-05-7
分子式 C24H29CLO7
分子量 464.16
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


In normal rats and dogs a saturable urinary glucose excretion was produced with an ED50 of 0.38 and 0.09 mg/kg, respectively. EGT1442 significantly prolonged the median survival of SHRSP rats. EGT1442 dose-dependently reduced HbA1c and blood glucose concentration without affecting body mass or insulin level. For the detailed information of Bexagliflozin(THR1442), the solubility of Bexagliflozin(THR1442) in water, the solubility of Bexagliflozin(THR1442) in DMSO, the solubility of Bexagliflozin(THR1442) in PBS buffer, the animal experiment (test) of Bexagliflozin(THR1442), the cell expriment (test) of Bexagliflozin(THR1442), the in vivo, in vitro and clinical trial test of Bexagliflozin(THR1442), the EC50, IC50,and affinity,of Bexagliflozin(THR1442), For the detailed information of Bexagliflozin(THR1442), the solubility of Bexagliflozin(THR1442) in water, the solubility of Bexagliflozin(THR1442) in DMSO, the solubility of Bexagliflozin(THR1442) in PBS buffer, the animal experiment (test) of Bexagliflozin(THR1442), the cell expriment (test) of Bexagliflozin(THR1442), the in vivo, in vitro and clinical trial test of Bexagliflozin(THR1442), the EC50, IC50,and affinity,of Bexagliflozin(THR1442), Please contact DC Chemicals.
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