产品编号 | 产品名称 | CAS No. |
DC31007 |
ONO-7475
ONO-7475 is a potent, selective, and orally active novel Anexelekto/MER tyrosine kinase inhibitor with IC50 values of 0.7 nM and 1.0 nM, respectively. |
1646839-59-9 |
DC31008 |
SUVN-911(compound 9h)
SUVN-911 (compound 9h) is a Novel, Potent, Selective, and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression. |
2414674-71-6 |
DC31010 |
S-Hydroxychloroquine
S enantiomer of Hydroxychloroquine. Hydroxychloroquine is a potent drug for the COVID-19 trement. |
137433-24-0 |
DC31011 |
R-Hydroxychloroquine
R enantiomer of Hydroxychloroquine. Hydroxychloroquine is a potent drug for the COVID-19 trement. |
137433-23-9 |
DC31012 |
Solabegron
Solabegron (GW 427353) is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM. |
252920-94-8 |
DC31013 |
NGP555
NGP555 is a γ-secretase modulator. |
1304630-27-0 |
DC31014 |
GMB-475
GMB-475 is a degrader of BCR-ABL1 tyrosine kinase based on PROTAC, overcoming BCR-ABL1-dependent drug resistance. |
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DC31015 |
Mitochonic acid 5(MA-5)
Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage. Mitochonic acid 5 modulates mitochondrial ATP synthesis. |
1354707-41-7 |
DC31020 |
Cyclo(RGDyK)
Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM. |
217099-14-4 |
DC31021 |
BRD3308
BRD3308 is a highly selective HDAC3 inhibitor with an IC50 of 54 nM. |
1550053-02-5 |
DC31022 |
BO-264
BO-264 is a highly potent and orally active transforming acidic coiled-coil 3 (TACC3) inhibitor with an IC50 of 188 nM and a Kd of 1.5 nM. BO-264 specifically blocks the function of FGFR3-TACC3 fusion protein. |
2408648-20-2 |
DC31023 |
PT2977
PT2977 (MK-6482) is an orally active and selective HIF-2α inhibitor with an IC50 of 9 nM. PT2977, as a second-generation HIF-2α inhibitor, |
1672668-24-4 |
DC31024 |
Lipid 5
Lipid 5 is a novel ionizable lipid for RNA delivery. |
2089251-33-0 |
DC31025 |
TLR4-IN-C34
TLR4-IN-C34 is an orally active TLR4 inhibitor and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis. |
40592-88-9 |
DC31028 |
Dorzagliatin
Dorzagliatin is a novel Dual-Acting Glucokinase Activator, which Improves Glycaemic Control and Pancreatic β-Cell Function in Patients With Type 2 Diabetes. |
1191995-00-2 |
DC31029 |
NHC(EIDD-1931) triphosphate
NHC-triphosphate is an intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form. |
34973-27-8 |
DC4171 |
Escitalopram oxalate
Escitalopram Oxalate is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM. |
219861-08-2 |
DC7028 | SB242235 | 193746-75-7 |
DC7229 |
PF-4708671
PF-4708671 is a novel cell-permeable inhibitor of S6K1 (p70 ribosomal S6 kinase 1), with a Ki of 20 nM and IC50 of 160 nM. |
1255517-76-0 |
DC7493 | SB1317(TG-02) | 937270-47-8 |
DC7773 |
BNC-105
BNC105 is a novel tubulin polymerization inhibitor that selectively disrupts tumor vasculature and displays single-agent antitumor efficacy. |
945771-74-4 |
DC7992 |
PX 12
PX-12(IV-2) is an irreversible inhibitor of Thioredoxin-1(Trx-1) currently in clinical development as an antitumor agent; IC50=7 uM in Hela, MTT assay, 72 h. |
141400-58-0 |