产品编号 | 产品名称 | CAS No. |
DC26058 |
Cathepsin L inhibitor III
Z-Phe-Tyr(tBu)-diazomethylketone is an inhibitor of cathepsin L |
114014-15-2 |
DC26061 |
Questiomycin A
Questiomycin A is a phenoxazine and a chromophore that has been found in Streptomyces and has antibacterial and anticancer activities. |
1916-59-2 |
DC26063 |
STING Agonist C11
STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway. |
875863-22-2 |
DC26064 |
YW1159
YW1159 is an inhibitor of Wnt signaling with an IC50 value of 1.2 nM in a reporter assay. |
2131223-69-1 |
DC26065 |
AT-127
AT-127 is a novel potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 1.18 nM. |
2099680-72-3 |
DC26066 |
BAY 61-3606 hydrochloride
BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase with Ki of 7.5 nM, displays no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. |
1615197-10-8 |
DC26071 |
BMS 814580
A highly potent, subtype-selective melanin concentrating hormone receptor 1 (MCHR1) inhibitor with Ki of 17 nM, without inhibitory activity for MCHR2 at 10 uM. |
1197420-11-3 |
DC26077 |
EG00229
The first small molecule ligand for the VEGF-A receptor neuropilin 1 (NRP1). |
1210945-69-9 |
DC26078 |
GNE-616
GNE-616 (GNE616) is a highly potent, metabolically stable, subtype selective inhibitor of Nav1.7 with Ki of 0.79 nM (hNav1.7). |
2244895-99-4 |
DC26079 |
GW 803430
A potent, specific, orally active melanin concentrating hormone receptor 1 (MCHR1) inhibitor with kI of 3.8 nM, >100-fold selectivity over a battery of GPCRs, ion channels and enzymes. |
515141-51-2 |
DC26080 |
GX-674
GX-674 is a potent, selective Nav1.7 inhibitor with IC50 of 0.1 nM. |
1432913-36-4 |
DC26081 |
JTE-852
JTE-852 is a novel potent, selective, ATP-competitive Syk kinase inhibitor with IC50 of 1.25/1.28 nM for human/rat Syk, respectively. |
909283-40-5 |
DC26091 |
PF-05198007
PF-05198007 is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 9 nM, no significant activity against Nav1.5 (IC50>10 uM). |
1235406-19-5 |
DC26097 |
SR-14150
SR-14150 is a potent NOP/μ-opioid partial agonist with Ki of 1.39 nM and 29.9 nM, respectively. |
709024-69-1 |
DC26100 |
SR-16507
SR-16507 is a potent full agonist of ORL1 receptor (NOP receptor) and partial agonist of mu-opioid receptor with Ki of 5.22 nM and 1.07 nM, respectively. |
1207195-44-5 |
DC26109 |
MCL0129 tetrahydrochloride
MCL0129 is a selective, potent melanocortin-4 receptor (MC4R) antagonist with Ki of 7.9 nM, without affinity for MC1 and MC3. |
574001-66-4 |
DC26113 |
LSP4–2022
LSP4–2022 is a novel potent, selective, brain-penetrant mGluR4 agonist with EC50 of 0.11 uM in cell-based assays. |
1413405-33-0 |
DC26114 |
GpTx-1
GpTx-1 is a potent, selective, 34-residue peptide antagonist of Nav1.7 sodium channel with IC50 of 10 nM, displays 20- and 1000- fold selectivity over NaV1.4 and NaV1.5.. |
1661050-12-9 |
DC26116 |
Poloppin
Poloppin is a cell-active, small molecule inhibitor of protein-protein interaction via the Polo-box domain (PBD) of the mitotic Polo-like kinase (PLK) with IC50 of 26.9 uM (PLK1) in FP assays. |
683808-78-8 |
DC26139 |
2-(5-Chloro-1H-indol-2-yl)acetic acid
2-(5-Chloro-1H-indol-2-yl)acetic acid|CAS 720000-48-6 |
720000-48-6 |
DC26151 |
Naloxone (hydrochloride)
Naloxone is an opioid inverse agonist drug used to counter the effects of opiate overdose. |
357-08-4 |
DC26155 |
Sulfaphenazole
Sulfaphenazole is an inhibitor of CYP2C9 (Ki = 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Kis = 63 and 29 μM for CYP2C8 and CYP2C18, respectively, and no activity at CYP1A1, CYP1A2, CYP3A4, CYP2C19). |
526-08-9 |