Ezutromid是一个小分子utrophin的调制剂。

Lusutrombopag 是一种可口服的血小板生成素受体 (thrombopoietin receptor) 激动剂，用于治疗慢性肝病。

Deferasirox (ICL 670) 是具有口活性的，用于治疗铁离子过量的螯合剂。

Danicopan (ACH-4471,) is a highly potent, orally active Factor D inhibitor with Kd of 0.54 nM.

A potent, selective, orally availale C5aR (CD88) inhibitor with IC50 of 0.1 nM.

Sivelestat(ONO5046; LY544349; EI546) is a competitive inhibitor of human neutrophil elastase(IC50 = 44 nM; Ki=200 nM); also inhibited leukocyte elastase obtained from rabbit, rat, hamster and mouse.

Benzbromarone is a highly effective and well tolerated non-competitive inhibitor of xanthine oxidase, used as an uricosuric agent, used in the treatment of gout.

Senicapoc(ICA17043) is a potent and selective Gardos channel blocker; blocked Ca(2+)-induced rubidium flux from human RBCs/ inhibited RBC dehydration with IC50s of 11 nM/30 nM, respectively. IC50 value: 11/30 nM [1] Target: Gardos channel in vitro: I

Desogestrel(Org-2969) is a third-generation 19-nortestosterone derivative progestogen; is contained in many oral contraceptive preparations, both combined (COCs) to ethinyl-estradiol (EE) or alone in a progestin-only pill (POP).

GAL-021 is a new intravenous BKCa-channel blocker.