产品编号 | 产品名称 | CAS No. |
DC1012 |
Macitentan (Actelion-1,ACT-064992)
macitentan (Actelion-1, ACT-064992) is an orally active, non-peptide dual endothelin (ET)A/B receptor antagonist with IC50 of 0.5 nM/391 nM. |
441798-33-0 |
DC10563 |
E-7046
E7046 is an orally bioavailable and specific EP4 antagonist, with IC50 of 13.5 nM and Ki of 23.14 nM, exhibiting anti-tumor activities. |
1369489-71-3 |
DC10630 |
ONO-7300243
ONO-7300243 is a novel, potent LPA1(Lysophosphatidic Acid Receptor) antagonist with an IC50 of 160 nM. |
638132-34-0 |
DC4102 |
SB269970
SB269970 is a potent and selective 5-HT7 receptor antagonist. |
201038-74-6 |
DC4108 |
Sitaxentan sodium
Sitaxentan sodium (TBC-11251) is a selective endothelin receptor-A antagonist with IC50 and Ki of 1.4 nM and 0.43 nM, respectively. |
210421-74-2 |
DC4201 |
Fosaprepitant dimeglumine
Fosaprepitant (MK-0517, L-758,298) is a water-soluble phosphoryl prodrug for Aprepitant which is a NK1 antagonist. |
265121-04-8 |
DC7192 |
LY-404039
LY404039 is an inhibitor for mGluR1(Ki=149 nM) and mGluR2(Ki= 92 nM), which can also inhibit dopamine receptor. |
635318-11-5 |
DC7494 |
SB-242084 HCl
5-HT2C receptor antagonist that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2Breceptors respectively. Also displays selectivity over a range of other 5-HT, dopamine and adrenergic receptors. Brain penetrant; exerts anxiolytic-like activity. |
1049747-87-6 |
DC7513 |
TCS 1102
TCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3 nM for OX2 and OX1 receptors respectively). |
916141-36-1 |
DC7710 |
Lasmiditan (COL-144; LY573144)
Lasmiditan (COL-144; LY573144) is a high-affinity, highly selective 5-HT1F receptor agonist(Ki=2.1 nM), compared with Ki of 1043 nM and 1357 nM at the 5-HT(1B) and 5-HT(1D) receptors, respectively. |
439239-90-4 |
DC7867 |
AMG-837
AMG 837 is a potent GPR40 agonist(EC50=13 nM) with a superior pharmacokinetic profile and robust glucose-dependent stimulation of insulin secretion in rodents. |
865231-46-5 |
DC8435 |
LY2119620
LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors. |
886047-22-9 |
DC8471 |
CGS 21680 hydrochloride
CGS 21680 hydrochloride is an A2A adenosine receptor agonist (Ki = 27 nM). |
124431-80-7 |
DC8623 |
AM966
AM966 is a high affinity, selective, oral LPA1 (lysophosphatidic acid receptor, IC50=17 nM) antagonist, with selectivity for this receptor over the other LPA receptors. |
1228690-19-4 |
DC8755 | WAY 100635 Hydrochloride | 146714-97-8 |
DC8779 |
Glycopyrrolate
Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic. |
596-51-0 |
DC8876 |
Rimonabant(SR141716)
Rimonabant(SR141716) is a selective central cannabinoid (CB1) receptor inverse agonist with Ki of 1.8 nM. |
168273-06-1 |
DC8925 |
Atipamezole
Atipamezole(MPV1248) is an alpha-adrenoceptor antagonist with high affinity and selectivity for the alpha 2-receptor. |
104054-27-5 |
DC9059 |
Olanzapine
Olanzapine in stock,price: 300 USD/1G. Olanzapine(LY170053) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist. |
132539-06-1 |
DC9153 |
Losartan Potassium
Losartan is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. |
124750-99-8 |
DCAPI1080 |
Istradefylline (KW-6002)
Istradefylline(KW6002) is a very potent, selective and orally active adenosine A2A receptor antagonist(Ki=2.2 nM) in experimental models of Parkinson's disease. |
155270-99-8 |
DCAPI1411 |
Bisoprolol Fumarate
(±)-Bisoprolol hemifumarate is a selective β1-AR adrenergic antagonist. Possesses β1/β2 selectivity of approximately 100-fold and a Kd of 2-3 nM at the β1-AR (β1 receptor). |
104344-23-2 |