MK-8998
产品编号: DC9993
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应用领域
MK-8998 (compound 33) 是有效的，选择性的T型钙通道抑制剂。
| Cas No.: |
953778-58-0 |
| 名称: |
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| 别名: |
MK8998,MK 8998 |
| SMILES: |
CC(C)C1=CC=C(CC(N[C@H](C)C2=NC=C(OCC(F)(F)F)C=C2)=O)C=C1 |
| 分子式: |
C20H23F3N2O2 |
| 分子量: |
380.17 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vivo: |
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| In Vitro: |
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| References: |
Src kinase inhibitor I is a potent competitive inhibitor of both Src and Lck (IC50 = 44 and 88 nM, respectively), as well as Csk and Yes.It less effectively blocks the receptor tyrosine kinases VEGFR2 and C-fms (IC50 = 0.32 and 30 µM), as well as a long list of serine/threonine kinases.Src Kinase Inhibitor I also inhibits receptor-interacting protein-2 with an IC50 value of 26 nM. |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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询盘
