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Remodelin is a 2-thiazolylhydrazone derivative that, at 10 µM, improves nuclear architecture, chromatin organization, and survival of both cells lacking lamin A and cells from patients with progeria.1 Remodelin is an inhibitor of N-acetyltransferase 10 (NAT10), which acetylates both histones and microtubules.1 Mutation of NAT10 mimics the effects of remodelin on nuclear morphology, suggesting that these effects of remodelin require NAT10.1 Remodelin also has cytotoxic effects against some species of the fungus Candida.. For the detailed information of Remodelin (hydrobromide) , the solubility of Remodelin (hydrobromide) in water, the solubility of Remodelin (hydrobromide) in DMSO, the solubility of Remodelin (hydrobromide) in PBS buffer, the animal experiment (test) of Remodelin (hydrobromide) , the cell expriment (test) of Remodelin (hydrobromide) , the in vivo, in vitro and clinical trial test of Remodelin (hydrobromide) , the EC50, IC50,and affinity,of Remodelin (hydrobromide) , Please contact DC Chemicals. |
