Cas No.: | 945526-43-2 |
名称: | 4-(1,1-dimethylethyl)-N-[4-(1H-imidazol-1-yl)phenyl]-benzenesulfonamide |
别名: | c-Kit Inhibitor II |
SMILES: | O=S(C1=CC=C(C(C)(C)C)C=C1)(NC2=CC=C(N3C=CN=C3)C=C2)=O |
分子式: | C19H21N3O2S |
分子量: | 355.5 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | ISCK03 (inhibitor of SCF/KIT) is a cell-permeable phenyl-imidazolosulfonamide compound that inhibits KIT activity. ISCK03 inhibits SCF-induced KIT phosphorylation and downstream ERK phosphorylation at a concentration of 1 - 5 µM in 501mel melanoma cells (Na et al.). |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
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