Guadecitabine(SGI-110)
产品编号: DC6313
Featured
我们的合作伙伴:
中国地区超过5000个高品质化合物库存
应用领域
Guadecitabine (SGI-110) 是 DNA 甲基转移酶 (DNMT) 的抑制剂。
Cas No.: |
929901-49-5 |
名称: |
|
别名: |
SGI110,SGI 110 |
SMILES: |
O=C1C2=C(N([C@H]3C[C@H](O)[C@@H](COP(O)(O[C@@H]4[C@@H](CO)O[C@@H](N5C=NC(N)=NC5=O)C4)=O)O3)C=N2)NC(N)=N1 |
分子式: |
C18H23N9NaO10P |
分子量: |
579.39 |
纯度: |
|
保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
|
In Vivo: |
|
In Vitro: |
|
References: |
SGI-110 is a 5-aza-2’-deoxycytidine-containing demethylating dinucleotide, which works via a mechanism similar to that of 5-aza-CdR after incorporation of its aza-moiety into DNA. However, SGI-110 is well protected from deamination by cytidine deaminase. |
Kinase Assay: |
|
Cell Assay: |
|
Animal Administration: |
|
References: |
|
MSDS
TITLE |
DOWNLOAD |
MSDS_1487_DC6313_929901-49-5 |
|
COA
LOT NO. |
DOWNLOAD |
|
|
询盘