PLK1 inhibitor GSK461364
产品编号: DC8598
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应用领域
GSK461364 是选择性，可逆，ATP竞争性的 PLK1 抑制剂，Ki 值为 2.2 nM。
| Cas No.: |
929095-18-1 |
| 名称: |
(R)-5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide |
| 别名: |
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| SMILES: |
CN1CCN(CC2=CC3N(C4SC(C(N)=O)=C(OC(C5C=CC=CC=5C(F)(F)F)C)C=4)C=NC=3C=C2)CC1 |
| 分子式: |
C27H28F3N5O2S |
| 分子量: |
543.6 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
GSK461364 is a potent small molecule Polo-like kinase 1 (PLK1) inhibitor with a Ki of 2.2 nM.
in vitro: GSK461364 is a potent inhibitor of cell proliferation causing 50% growth inhibition (GI50) below 100 nM in most of the cell lines tested with limited t |
| Kinase Assay: |
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| Cell Assay: |
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| Animal Administration: |
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| References: |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_3119_DC8598_929095-18-1 |
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COA
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DOWNLOAD |
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