Cas No.: | 929016-96-6 |
名称: | (E)-3-(2-butyl-1-(2-(diethylamino)ethyl)-1H-benzo[d]imidazol-5-yl)-N-hydroxyacrylamide |
别名: | SB939; SB-939; SB 939 |
SMILES: | C(NO)(=O)/C=C/C1=CC=C2C(=C1)N=C(CCCC)N2CCN(CC)CC |
分子式: | C20H30N4O2 |
分子量: | 358.48 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
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In Vitro: | |
References: | SB939 has a 100-fold greater selectivity For HDACs than For Zn-binding non-HDAC enzymes, receptors, and ion channels. SB939 is a potent inhibitor of HDAC class I isoenzymes, HDAC1, HDAC2, HDAC3 and HDAC8 with the IC50 values ranging from 43 nM to 140 nM |
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Animal Administration: | |
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