Cas No.: | 925701-46-8 |
名称: | 2-((2S,6R)-2,6-dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide |
别名: | KU60019; KU 60019 |
SMILES: | C(NC1C=CC2SC3=C(CC=2C=1)C=CC=C3C1OC(N2CCOCC2)=CC(=O)C=1)(=O)CN1C[C@H](C)O[C@H](C)C1 |
分子式: | C30H33N3O5S |
分子量: | 547.67 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
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In Vitro: | |
References: | Compared to KU-55933, KU-60019 is an improved more water-soluble inhibitor of the ATM kinase, while displaying similar target selectivity. KU-60019 has little activity against DNA-PKcs and ATR with IC50 values of 1.7 μM and >10 μM, respectively, as well a |
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Animal Administration: | |
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