Cas No.: | 923032-37-5 |
名称: | |
别名: | BAY 869766, BAY 86-9766 |
SMILES: | O=S(C1(C[C@H](O)CO)CC1)(NC(C(NC(C(F)=C2)=CC=C2I)=C3F)=C(OC)C=C3F)=O |
分子式: | C19H20F3In2O5S |
分子量: | 572.34 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | RDEA119 is selectively bound directly to an allosteric pocket in the MEK1/2 enzymes, and highly efficacious at inhibiting cell proliferation in several tumor cell lines, including A375, SK-MEI-28, Colo205, HT-29 and BxPC3. RDEA119 inhibits anchorage-depen |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |