Cas No.: | 920022-47-5 |
名称: | |
别名: | RO-5028442; RO 5028442; RO5028442 |
SMILES: | O=C(C1=CN(CCN(C)C)C2=C1C=CC(Cl)=C2)N3CCC4(CC3)OCC5=C4C=CC=C5 |
分子式: | C25H28ClN3O2 |
分子量: | 437.96 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | In Vitro: Compounds 29, 31, and RO5028442 (compound 8) have excellent binding in and functional affinity for hV1a, moderate mouse affinity, and excellent selectivity versus human V2 (hV2) and human oxytocin (hOT) receptors. All compounds show high solubility. RO5028442 is found to be highly selective against a panel of 89 targets. Finally, RO5028442 is identified as a suitable compound for clinical studies. |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |