ABC294640(Opaganib)
产品编号: DC5027
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应用领域
Opaganib (ABC294640) 是一种选择性的竞争性的鞘氨醇激酶 2 (SK2) 抑制剂,Ki 为 9.8 μM。
Cas No.: |
915385-81-8 |
名称: |
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别名: |
ABC294640; ABC-294640; ABC 294640; 3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide,Opaganib |
SMILES: |
C(C(NCC1C=CN=CC=1)=O)12CC3CC(CC(C4=CC=C(Cl)C=C4)(C3)C1)C2 |
分子式: |
C23H25ClN2O |
分子量: |
380.91 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vitro: |
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References: |
ABC294640 is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preventing the phosphor |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
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MSDS_1404_DC5027_915385-81-8 |
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