Veliparib (ABT-888 hydrochloride)
产品编号: DC5150
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应用领域
Veliparib dihydrochloride是有效的 PARP1 和 PARP2 抑制剂,Ki 分别为5.2 nM,2.9 nM。
Cas No.: |
912445-05-7 |
名称: |
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别名: |
ABT 888,ABT888 |
SMILES: |
C[C@@]1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N |
分子式: |
C13H18Cl2N4O |
分子量: |
317.21 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
Veliparib (ABT-888) is a poly(ADP-ribose) polymerase (PARP) -1 and -2 inhibitor with chemosensitizing and antitumor activities. With no antiproliferative effects as a single agent at therapeutic concentrations, ABT-888 inhibits PARPs, thereby inhibiting D |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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