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Qstatin

产品编号: DC11160
Qstatin
结构式
902688-24-8
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中国地区超过5000个高品质化合物库存
应用领域
QStatin 是一种有效且选择性的 SmcR 抑制剂 (V. harveyi LuxR 同源物)，EC50 值为 208.9 nM，与 SmcR 紧密结合并改变了蛋白质的柔韧性，从而改变了其转录调控活性。QStatin 在多种弧菌中显示 pan-QS 抑制剂活性，并减弱其在水生宿主中的毒力。QStatin 可用于水产养殖的可持续性抗弧菌病药物。
化学性质生物活性化合物的使用COA & MSDS相关产品产品说明书
Cas No.: 902688-24-8
名称: 1-(5-bromothiophene-2-sulfonyl)-1H-pyrazole
别名:
SMILES: N(S(C1SC(Br)=CC=1)(=O)=O)1C=CC=N1
分子式: C7H5BrN2O2S2
分子量: 293.153
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: Qstatin is a potent SmcR inhibitor in V. vulnificus. with IC50 of 208.9 nM, shows pan-QS (quorum sensing) inhibitor activity in diverse Vibrio species; binds tightly to a putative ligand-binding pocket on SmcR, the LuxR homologue in V. vulnificus, and affects expression of QS-regulated genes.QStatin attenuates representative QS-regulated phenotypes in various Vibrio speciesbinds tightly to a putative ligand-binding pocket in SmcR and changes the flexibility of the protein, thereby altering its transcription regulatory activity. QStatin may be a sustainable antivibriosis agent useful in aquacultures.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
TITLE DOWNLOAD
MSDS_690_DC11160_902688-24-8
COA
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