| References: |
T-00127-HEV1 inhibited PI4KB activity with a higher specificity for than other PI kinases, in contrast to GW5074, which had a broad specificity for PI . T-00127-HEV1 and GW5074 did not inhibit hepatitis C virus (HCV) replication, in contrast to a strong inhibitory effect of AN-12-H5. PI4KB is an enterovirus-specific host factor required for the replication process and targeted by some enviroxime-like compounds (T-00127-HEV1 and GW5074) and that enviroxime-like compounds may have targets other than PI kinases for their antiviral effect. For the detailed information of T-00127-HEV1, the solubility of T-00127-HEV1 in water, the solubility of T-00127-HEV1 in DMSO, the solubility of T-00127-HEV1 in PBS buffer, the animal experiment (test) of T-00127-HEV1, the cell expriment (test) of T-00127-HEV1, the in vivo, in vitro and clinical trial test of T-00127-HEV1, the EC50, IC50,and affinity,of T-00127-HEV1, For the detailed information of T-00127-HEV1, the solubility of T-00127-HEV1 in water, the solubility of T-00127-HEV1 in DMSO, the solubility of T-00127-HEV1 in PBS buffer, the animal experiment (test) of T-00127-HEV1, the cell expriment (test) of T-00127-HEV1, the in vivo, in vitro and clinical trial test of T-00127-HEV1, the EC50, IC50,and affinity,of T-00127-HEV1, Please contact DC Chemicals. |
