Cas No.: | 900185-02-6 |
名称: | 2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one |
别名: | PIK294,PIK 294 |
SMILES: | N1C2=C(C(C)=CC=C2)C(=O)N(C2=CC=CC=C2C)C=1CN1C2C(C(C3=CC=CC(O)=C3)=N1)=C(N)N=CN=2 |
分子式: | C28H23N7O2 |
分子量: | 489.53 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | PIK-294 shows distinct patterns of iso Form selectivity to inhibit different subsets of class I PI3K iso Forms (p110β, p110δ, and p110γ) and exhibits low sensitivity to p110α with IC50 of 10 μM). The m-phenol moiety of PIK-294 is able to penetrate the dee |
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Animal Administration: | |
References: |