BMH-21
产品编号: DC7959
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应用领域
BMH-21是一新型DNA嵌入剂(DNA intercalator),能结合rDNA并抑制RNA polymerase I的转录,不使组蛋白H2AX磷酸化。
Cas No.: |
896705-16-1 |
名称: |
N-[2-(Dimethylamino)ethyl]-12-oxo-2H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide |
别名: |
BMH 21,BMH21 |
SMILES: |
CN(C)CCNC(=O)C1=CC=CN2C1=NC3=CC4=CC=CC=C4C=C3C2=O |
分子式: |
C21H20N4O2 |
分子量: |
360.41 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
BMH-21 effects on the nucleolar stress response were independent of major DNA damage associated PI3-kinase pathways, ATM, ATR and DNA-PKcs. BMH-21 is a chemically unique DNA intercalator that has high bioactivity towards Pol I inhibition without activatio |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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