MF63
产品编号: DC7651
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应用领域
MF63是mPGES-1抑制剂,对猪mPGES-1和人mPGES-1的IC50分别为0.9 nM和1.3 nM。
Cas No.: |
892549-43-8 |
名称: |
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别名: |
MF 63; MF-63 |
SMILES: |
C1=CC=C2C(=C1)C3=C(C=CC(=C3)Cl)C4=C2N=C(N4)C5=C(C=CC=C5C#N)C#N |
分子式: |
C23H11ClN4 |
分子量: |
378.81 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
MF63 is a selective mPGES-1 inhibitor with an IC50 of 0.9 nM and 1.3 nM For pig mPGES-1 and human mPGES-1 enzyme, respectively. MF63 potently inhibited the human mPGES-1 enzyme with a high degree (>1000-fold) of selectivity over other prostanoid synthase |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
TITLE |
DOWNLOAD |
MSDS_1875_DC7651_892549-43-8 |
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COA
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