Cas No.: | 887375-67-9 |
名称: | |
别名: | K 115; K115 |
SMILES: | FC1=CN=CC2=C1C(S(N3CCCNC[C@@H]3C)(=O)=O)=CC=C2.[H]Cl.O.O |
分子式: | C15H23ClFN3O4S |
分子量: | 395.88 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | K-115, an isoquinolinesulfonamide compound, is a highly selective and potent (IC50 = 31 nM) Rho-kinase inhibitor; is in Phase II clinical development in patients with POAG or ocular hypertension. IC50 value: 31 nM Target: ROCK inhibitor K-115 had selecti |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |