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GW-9508

产品编号: DC1086 Featured
GW-9508
结构式
885101-89-3
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中国地区超过5000个高品质化合物库存
应用领域
GW9508 是一种有效的选择性 G 蛋白偶联受体 FFA1 (GPR40) 和 GPR40 激动剂，pEC50 值分别为 7.32 和 5.46。GW9508 对 GPR40 的选择性是 GPR120 的 100 倍左右，对其他 GPCR，激酶，蛋白酶，整联蛋白和 PPAR 无活性。GW9508 是一种葡萄糖敏感性胰岛素促分泌剂和 ATP 敏感性钾 (KATP) 通道开放剂。GW9508 具有抗炎和抗动脉粥样硬化活性。
化学性质生物活性化合物的使用COA & MSDS相关产品产品说明书
Cas No.: 885101-89-3
名称: Benzenepropanoic acid, 4-[[(3-phenoxyphenyl)methyl]amino]-
别名: GW-9508,GW9508,GW 9508
SMILES: C(CCC(O)=O)1=CC=C(NCC2=CC=CC(OC3=CC=CC=C3)=C2)C=C1
分子式: C22H21NO3
分子量: 347.41
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: GW9508 is a potent and selective agonist For the free fatty acid receptor FFA1 (GPR40) (pEC50 values are 7.32, < 4.3 and < 4.3 For FFA1, FFA2 and FFA3 receptors respectively). Inactive against a range of other GPCRs, kinases, proteases, integrins and PPARs. Potentiates glucose-stimulated insulin secretion in MIN6 cells (pEC50 = 6.14). For the detailed information about the solubility of GW9508 in water, the solubility of GW9508 in DMSO, the solubility of GW9508 in PBS buffer, the animal experiment（test） of GW9508,the in vivo,in vitro and clinical trial test of GW9508,the cell experiment（test） of GW9508,the IC50, EC50 and Affinity of GW9508, please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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