Cas No.: | 879127-16-9 |
名称: | N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-cyclopropanecarboxamide |
别名: | AKI-7169,AKI 7169,AKI7169 |
SMILES: | O=C(C1CC1)NC2=CC=CC(NC3=NC=CC(NC4=CC=CC(C(F)(F)F)=C4)=N3)=C2 |
分子式: | C21H18F3N5O |
分子量: | 413.4 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM). It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR (IC50s = 386, 3,550, 591, 1,980, 2,510, 887, and >10,000 nM, respectively). |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |