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应用领域
TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 μM, 1.11 μM and 0.26 μM, respectively.
Cas No.: |
877877-35-5 |
名称: |
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别名: |
TW37,TW 37 |
SMILES: |
O=C(C1=CC(CC2=CC=CC=C2C(C)C)=C(C(O)=C1O)O)NC3=CC=C(C=C3)S(=O)(C4=CC=CC=C4C(C)(C)C)=O |
分子式: |
C33H35NO6S |
分子量: |
573.7 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 μM, 1.11 μM and 0.26 μM, respectively.
IC50 Value: 0.29 μM (Ki for Bcl-2)
Target: Bcl-2 Family
in vitro: TW-37 shows significant anti-proliferative and pro-apopto |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
TITLE |
DOWNLOAD |
MSDS_3384_DC5005_877877-35-5 |
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