SC-66
产品编号: DC9273
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应用领域
SC66 是一种 Akt 抑制剂,降低细胞活力,这种作用存在剂量和时间依赖性,且抑制肝癌 (HCC) 细胞的集落形成和诱导凋亡。
Cas No.: |
871361-88-5 |
名称: |
(2E,6E)-2,6-Bis(4-pyridinylmethylene)cyclohexanone |
别名: |
SC66,SC 66 |
SMILES: |
C(=O)1/C(=C/C2C=CN=CC=2)/CCC/C/1=C\C1C=CN=CC=1 |
分子式: |
C18H16N2O |
分子量: |
276.33 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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In Vivo: |
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In Vitro: |
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References: |
Allosteric inhibitor of Akt; interferes with pleckstrin homology domain binding to PIP3 and facilitates Akt ubiquitination. Exhibits anticancer activity in vitro and in vivo. |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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References: |
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MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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