Linsitinib(OSI-906)
产品编号: DC4105
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应用领域
Linsitinib (OSI-906) 是 IGF-1 和胰岛素受体的双重抑制剂,IC50 分别为35 和 75 nM。
Cas No.: |
867160-71-2 |
名称: |
(1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutanol |
别名: |
OSI 906,OSI906 |
SMILES: |
CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O |
分子式: |
C26H23N5O |
分子量: |
421.49 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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References: |
Linsitinib (OSI-906): Linsitinib (OSI-906) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. OSI-906 selectively inhibits IGF-1R, which may result in the inhibi |
Kinase Assay: |
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Cell Assay: |
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Animal Administration: |
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MSDS
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MSDS_1350_DC4105_867160-71-2 |
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