Dorsomorphin(BML-275)
产品编号: DC8296
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应用领域
Dorsomorphin (BML-275; Compound C) 是一种选择性,ATP 竞争性的 AMPK 抑制剂 (在没有 AMP 的情况下,Ki 为 109 nM)。Dorsomorphin 选择性抑制 BMP I 型受体 ALK2,ALK3 和 ALK6。Dorsomorphin 诱导自噬 (autophagy) 作用。
Cas No.: |
866405-64-3 |
名称: |
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别名: |
(BML-275; Compound C; BML275; BML 275 |
SMILES: |
C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3 |
分子式: |
C24H25N5O |
分子量: |
399.49 |
纯度: |
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保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
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References: |
Dorsomorphin(Compound C; BML-275) has been shown to act as a potent and selective inhibitor of AMPK (AMP-activated protein kinase; Ki = 109 nM), induced by AICAR and metformin; also inhibits the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), B |
Kinase Assay: |
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Animal Administration: |
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MSDS
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MSDS_2252_DC8296_866405-64-3 |
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