Cas No.: | 865362-74-9 |
名称: | 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine |
别名: | FR 180204,FR-180204,FR180204 |
SMILES: | C1=CC=C(C=C1)C2=NN3C=CC=CC3=C2C4=CC5=C(NN=C5N=N4)N |
分子式: | C18H13N7 |
分子量: | 327.34 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | Selective ERK inhibitor (IC50 values are 0.14 and 0.31 μM For ERK2 and ERK1 respectively). Displays 30-fold selectivity For ERK over p38α (IC50 = 10 μM); displays no activity against human recombinant MEK1, MKK4, IKKα, PKCα, Src, Syc and PDGFα at concen |
Kinase Assay: | |
Cell Assay: | |
Animal Administration: | |
References: |