| Cas No.: | 864082-47-3 |
| 名称: | N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-(4-(trifluoromethyl)phenyl)-1,4,5,6-tetrahydropyridine-3-carboxamide |
| 别名: | GSK429286A,GSK-429286A,GSK 429286A |
| SMILES: | O=C(C(C(C1=CC=C(C(F)(F)F)C=C1)C2)=C(C)NC2=O)NC3=CC4=C(NN=C4)C=C3F |
| 分子式: | C21H16F4N4O2 |
| 分子量: | 432.37 |
| 纯度: | |
| 保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | |
| In Vivo: | |
| In Vitro: | |
| References: | GSK429286A slightly inhibits RSK and p70S6K with IC50 of 0.78 μM and 1.94 μM, respectively. GSK429286A significantly inhibits rat aortic ring dilation with IC50 of 190 nM. GSK429286A at 1 μM reduces ROCK2 activity over 20-fold, under conditions in which |
| Kinase Assay: | |
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| Animal Administration: | |
| References: |
MSDS
| TITLE | DOWNLOAD |
| MSDS_1583_DC7144_864082-47-3 |
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COA
| LOT NO. | DOWNLOAD |
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