WP1130(Degrasyn)
产品编号: DC7558
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应用领域
Degrasyn (WP1130) 是可渗透细胞的 去泛素化酶(DUB) 抑制剂，直接抑制USP9x，USP5，USP14和UCH37的DUB活性。 Degrasyn 减弱抗细胞凋亡蛋白 Bcr-Abl 和 JAK2。
| Cas No.: |
856243-80-6 |
| 名称: |
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| 别名: |
Degrasyn; WP 1130; WP-1130 |
| SMILES: |
CCC[C@@H](C1=CC=CC=C1)NC(=O)/C(=C/C2=NC(=CC=C2)Br)/C#N |
| 分子式: |
C19H18BrN3O |
| 分子量: |
384.27 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| References: |
WP1130 is a novel selective small molecular deubiquitinase (DUB) inhibitor and a Bcr/Abl destruction pathway activator with an IC50 of 1.8 μM For K562 cells.WP1130 is useful For anti-cancer and treatment of chronic myelogenous leukemia (CML)For the deta |
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MSDS
| TITLE |
DOWNLOAD |
| MSDS_1823_DC7558_856243-80-6 |
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COA
| LOT NO. |
DOWNLOAD |
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