Cas No.: | 850664-21-0 |
名称: | N-[3-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy]phenyl]-4-[2-(4-morpholinyl)ethoxy]benzamide |
别名: | |
SMILES: | CCN1C2=CC(OC3=CC=CC(NC(C4=CC=C(OCCN5CCOCC5)C=C4)=O)=C3)=NC=C2N=C1C6=NON=C6N |
分子式: | C29H30N8O5 |
分子量: | 570.6 |
纯度: | |
保存条件: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | |
In Vivo: | |
In Vitro: | |
References: | Potent Rho kinase (ROCK) inhibitor (IC50 values are 1.6 and 4 nM For recombinant human ROCK1 and ROCK2 respectively). Displays greater than 30-fold selectivity For ROCK against a panel of serine/threonine kinases. Induces vasorelaxation in preconstricte |
Kinase Assay: | |
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Animal Administration: | |
References: |