Bedaquiline (TMC207)

产品编号: DC2012 Featured
Bedaquiline (TMC207)
结构式
843663-66-1
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中国地区超过5000个高品质化合物库存
应用领域
Bedaquiline (TMC207) 是一种二芳基喹啉药物,通过同时靶向 c-亚基和 ε-亚基来抑制结核分枝杆菌 (Mtb) F1FO-ATP合酶。Bedaquiline 具有解偶联活性。Bedaquiline 有用于耐多药结核病的潜力。
Cas No.: 843663-66-1
名称:
别名: Bedaquiline, TMC-207
SMILES: CN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O
分子式: C32H31BrN2O2
分子量: 555.5
纯度:
保存条件: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description:
In Vivo:
In Vitro:
References: TMC207 is a first-in-class diarylquinoline compound with a novel mechanism of action, the inhibition of bacterial ATP synthase, and potent activity against drug-sensitive and drug-resistant TB. For the detailed information about the solubility of Bedaquiline (TMC207) in water, the solubility of Bedaquiline (TMC207) in DMSO, the solubility of Bedaquiline (TMC207) in PBS buffer, the animal experiment(test) of Bedaquiline (TMC207),the in vivo,in vitro and clinical trial test of Bedaquiline (TMC207),the cell experiment(test) of Bedaquiline (TMC207),the IC50, EC50 and Affinity of Bedaquiline (TMC207), please contact DC Chemicals.
Kinase Assay:
Cell Assay:
Animal Administration:
References:
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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