ML130
产品编号: DC10142
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应用领域
Nodinitib-1 (ML130;CID-1088438)是NOD1抑制剂，IC50值为0.56 μM。
| Cas No.: |
799264-47-4 |
| 名称: |
1-[(4-Methylphenyl)sulfonyl]-1H-benzimidazol-2-amine |
| 别名: |
ML-130,ML 130 |
| SMILES: |
CC1=CC=C(C=C1)S(=O)(=O)N2C3=CC=CC=C3N=C2N |
| 分子式: |
C14H13N3O2S |
| 分子量: |
287.34 |
| 纯度: |
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| 保存条件: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
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| In Vitro: |
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| References: |
ML-130 is a potent and selective inhibitor of NOD1; displays 36-fold selectivity for NOD1 over NOD2 (IC50 values are 0.56 and >20 μM for NOD1 and NOD2 respectively). ML-130 Inhibits NOD1-induced NF-κB activation in HEK293 cells with no cytotoxicity. Shown to alter subcellular targeting of NOD1; also thought to alter the conformation of NOD1 protein in vitro. |
| Kinase Assay: |
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| References: |
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MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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